Dental care for HIV positive women

This summer time was challenging due to data collection for my research project Prognostic implications of oral health status in HIV positive women.

Why focus on women? Women are often excluded  from studies or not enrolled in the studies for various reasons and now global epidemiological data shows that almost half of HIV positive individuals are female.

The situation in Russian Federation is similar. Russia has one of the largest HIV epidemics in Europe, with 589 581 registered cases and 58 633 new HIV cases in 2010(HIV Federal Center report), an incidence 20% higher than during the previous years. The prevalence of HIV-infection in the country is still dominated by men (64.9%), however, this gap is closing due to increased incidence among women in recent years. In fact, during the period 2004-2010, 41-43% of new HIV infections were among women, double the 20.6% among women in 2000. New cases among women are predominantly caused by heterosexual contact (64.7% of new cases), and among men the primary mode of transmission is injecting drug use (74.5% of new cases). There has also been a notable rise in HIV transmission during sexual contact among reproductive-age women, from 7.6% in 2006 to 38.0 % in 2010.

In St. Petersburg, the second largest city in Russia, 39 809 cases of HIV have been reported since 1987, including 13 144 women (33% of all cases). Consequently, St. Petersburg also has the unfortunate distinction having the most HIV-positive pregnancies in Russia.

The age group most affected by HIV infection is those 18 to 30 years of age. The majority of these patients are, or soon will be, in the secondary stage of disease progression with diverse clinical manifestations, and are seeking surgical, dermatovenerological, and dental care.

The total number of female patients visiting a dentist at the St. Petersburg City AIDS Center (CAC) has increased 71% from 255 (Jun-Dec2009) to 436 (Jun-Dec2010). The number of HIV-positive pregnant women has skyrocketed from 4 to121 during the same period.

Limited access to a full range of dental care services for HIV-infected women results in poor dental hygiene, a risk factor for transmission of oral bacteria, including cariogenic, as well as the risk to the fetus of premature delivery and low birth weight.

High caries prevalence  was observed with a few oral lesions . This may have a substantial impact on health and quality of life in this vulnerable population.

 

Next study focused on unmet dental needs among HIV positive women. The self-administered survey was developed to assess information about demographic and perceived oral health status, along with dental needs of HIV-positive women.

I will post links of the articles once they are accepted.

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About Anna Vinogradova

Dental care for HIV+,Hep B and C patients applying and coordinating implementation of grants received grant from the United States Agency for International Development(USAID)(2006) and MATRA grant from the Netherlands General Consulate and Ministry of Foreign Affairs(2006-2007) scholarships to XIV International AIDS Conference, Barcelona, Spain, 2002 and the 4th IAS Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2007), Sydney, Australia,2007 Publications Abstracts: -Oral cavity manifestations among HIV patients; -HIV among women drug users in Drop-in center and Bus for Harm Reduction at XIV International AIDS Conference, July 2002, Barcelona, Spain -Treatment of oral candidiasis at1st Medical Mycological Congress, February 2003, Moscow, Russia -Dynamics of epidemic process in St. Petersburg; -Analysis of HIV-1 gp41 HR1 and HR2 regions of Different genetic forms from Russia and in relation to natural resistance-associated mutations to T-20 and polymorphism at 3rd IAS Conference, July 2005, Rio de Janeiro, Brazil - Oral manifestations among HIV patients failing antiretroviral therapy at the 4th IAS Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2007), Sydney, Australia,2007 Journals: 1. Viral and Bacterial infections in immunocompromised patients “Infections of XXI century"(2001) 2.Oral lesions as a complication of HIV infection in dental scientific-practical journal Parodontology No.4(26) 2001 3. Oral candidiasis among HIV patients with various T(CD4) cells count in Parodontology No.1(26) 2003 4.Analysis of Drug-Resistance Associated Mutations in Treatment-Naïve Individuals Infected with Different Genetic Forms of HIV-1 Circulating in Countries of the Former Soviet Union. Journal of Medical Virology 77:337-344 (2005) http://www.linkedin.com/ppl/webprofile?gwp=&id=6649012&pvs=pp&authToken=dmp2&authType=name&locale=en_US&trk=ppro_geturl&lnk=sign_in
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